发明名称 |
IN SITU FORMING HYDROGEL AND BIOMEDICAL USE THEREOF |
摘要 |
<p>Disclosed are in situ-forming injectable hydrogel and medical uses thereof. In the in situ-forming injectable hydrogel two or more homogeneous or heterogeneous polymers are bonded to each other by a dehydrogenation reaction between phenol or aniline moieties on adjacent polymers, wherein a polymer backbone is grafted with a phenol or aniline moiety using a linker. In contrast to conventional hydrogel, the in situ-forming injectable hydrogel is superior in terms of in vivo stability and mechanical strength thanks to the introduction of a water-soluble polymer as a linker which leads to an improvement in the reactivity of phenol or aniline moieties. Having the advantage of superior bio stability and mechanical strength, the hydrogel finds a variety of applications in the biomedical field.</p> |
申请公布号 |
EP2448610(A2) |
申请公布日期 |
2012.05.09 |
申请号 |
EP20100794384 |
申请日期 |
2010.07.01 |
申请人 |
AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION |
发明人 |
PARK, KI-DONG;JOUNG, YOON-KI;PARK, KYUNG-MIN |
分类号 |
A61L27/52;A61F2/00;A61K9/00;A61L27/54 |
主分类号 |
A61L27/52 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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