发明名称 |
BIOASSAY METHOD FOR ANTIBODY AGAINST THYROID-STIMULATING HORMONE RECEPTOR, MEASUREMENT KIT FOR THE ANTIBODY, AND NOVEL GENETICALLY MODIFIED CELL FOR USE IN THE BIOASSAY METHOD OR THE MEASUREMENT KIT |
摘要 |
The present invention provides a method and a kit for assaying a TSH receptor antibody, which are easy to manipulate and are safe. Specifically, the present invention provides a composition comprising a genetically modified cell forced to co-express a TSH receptor, a cyclic nucleotide responsive calcium channel, and a luminescent protein aequorin. Use of the composition enables the assay of a TSH receptor antibody contained in a sample. |
申请公布号 |
EP2450430(A1) |
申请公布日期 |
2012.05.09 |
申请号 |
EP20100794054 |
申请日期 |
2010.06.24 |
申请人 |
OTSUKA PHARMACEUTICAL CO., LTD. |
发明人 |
ARAKI, NAOHIRO |
分类号 |
C12N5/00;C12N5/10;C12N15/09;C12Q1/02;G01N33/50;G01N33/68 |
主分类号 |
C12N5/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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