发明名称 BIOASSAY METHOD FOR ANTIBODY AGAINST THYROID-STIMULATING HORMONE RECEPTOR, MEASUREMENT KIT FOR THE ANTIBODY, AND NOVEL GENETICALLY MODIFIED CELL FOR USE IN THE BIOASSAY METHOD OR THE MEASUREMENT KIT
摘要 The present invention provides a method and a kit for assaying a TSH receptor antibody, which are easy to manipulate and are safe. Specifically, the present invention provides a composition comprising a genetically modified cell forced to co-express a TSH receptor, a cyclic nucleotide responsive calcium channel, and a luminescent protein aequorin. Use of the composition enables the assay of a TSH receptor antibody contained in a sample.
申请公布号 EP2450430(A1) 申请公布日期 2012.05.09
申请号 EP20100794054 申请日期 2010.06.24
申请人 OTSUKA PHARMACEUTICAL CO., LTD. 发明人 ARAKI, NAOHIRO
分类号 C12N5/00;C12N5/10;C12N15/09;C12Q1/02;G01N33/50;G01N33/68 主分类号 C12N5/00
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