发明名称 |
Single cell microinjection using flexible and compliant fluidic channels and electroosmotic dosage control |
摘要 |
A microinjection device for injecting a target cell with a reagent. The microinjection device includes a flexible substrate; a target supply channel formed in the flexible substrate for receiving the target cell; a reagent supply channel formed in the flexible substrate for receiving the reagent; a suction capillary mounted within a suction channel formed in the flexible substrate, the suction capillary providing suction to the target supply channel for immobilizing the target cell within the target supply channel; an injection needle mounted within a needle channel formed in the flexible substrate, the injection needle being movable between injected and un-injected positions by deforming at least a part of the flexible substrate; and a plurality of electrodes embedded in the flexible substrate, the plurality of electrodes creating a voltage potential across the injection needle to move the reagent into the target when the injection needle is in the injected position. |
申请公布号 |
US8173415(B2) |
申请公布日期 |
2012.05.08 |
申请号 |
US20090576766 |
申请日期 |
2009.10.09 |
申请人 |
NOORI ARASH;SELVAGANAPATHY PONNAMBALAM R.;MCMASTER UNIVERSITY |
发明人 |
NOORI ARASH;SELVAGANAPATHY PONNAMBALAM R. |
分类号 |
C12M1/00;C12M3/00 |
主分类号 |
C12M1/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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