发明名称 |
Sulfated oligosaccharide derivatives |
摘要 |
The invention relates to compounds which are polysulfated oligosaccharide derivatives having activity as inhibitors of heparan sulfate-binding proteins and inhibitors of the enzyme heparanase; methods for the preparation of the compounds; compositions comprising the compounds, and use of the compounds and compositions thereof for the antiangiogenic, antimetastatic, anti-inflammatory, antimicrobial, anticoagulant and/or antithrombotic treatment, lowering of blood triglyceride levels and inhibition of cardiovascular disease of a mammalian subject. |
申请公布号 |
US8173606(B2) |
申请公布日期 |
2012.05.08 |
申请号 |
US20100960145 |
申请日期 |
2010.12.03 |
申请人 |
FERRO VITO;FAIRWEATHER JON KRUEGER;KAROLI TOMISLAV;LIU LIGONG;PROGEN PHARMACEUTICALS LIMITED |
发明人 |
FERRO VITO;FAIRWEATHER JON KRUEGER;KAROLI TOMISLAV;LIU LIGONG |
分类号 |
A61K31/7034;A61K31/7016;A61K31/702;A61K31/7028;A61K31/7056;A61P7/02;A61P9/00;A61P29/00;A61P31/00;A61P35/00;A61P35/04;C07H3/04;C07H3/06;C07H5/04;C07H11/00;C07H15/04;C07H15/08;C07H15/18 |
主分类号 |
A61K31/7034 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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