发明名称 |
ABBREVIATED HCV THERAPY FOR HCV INFECTED PATIENTS WITH IL28B C/C GENOTYPE |
摘要 |
Disclosed herein is a method for administering an abbreviated hepatitis C virus (HCV) treatment regimen for an HCV-infected, rs12979860 single nucleotide polymorphism (SNP) (C/C) patient, which comprises: administering to said patient an effective amount of each of a direct-acting antiviral, pegylated interferon alfa-2a, and ribavirin; wherein the abbreviated HCV treatment regimen is less than 48 weeks. Also disclosed herein is a method of detecting an rs12979860 single nucleotide polymorphism (SNP) in a hepatitis C virus (HCV) infected patient comprising: detecting the rs12979860 SNP of chromosome 19 in a biological sample from a patient, wherein an rs12979860 SNP C/C patient is administered an abbreviated treatment regimen with a direct-acting antiviral agent in combination with peginterferon alfa-2a and ribavirin; and wherein the abbreviated HCV treatment regimen is less than 48 weeks.
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申请公布号 |
US2012107278(A1) |
申请公布日期 |
2012.05.03 |
申请号 |
US201113285444 |
申请日期 |
2011.10.31 |
申请人 |
BERREY MIRIAM MICHELLE;PRICE, JR. PETER SCHAEFER;SYMONDS WILLIAM T.;PHARMASSET, INC. |
发明人 |
BERREY MIRIAM MICHELLE;PRICE, JR. PETER SCHAEFER;SYMONDS WILLIAM T. |
分类号 |
A61K38/21;A61P31/14;C12Q1/70 |
主分类号 |
A61K38/21 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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