发明名称 |
TREATMENT OF DOWN SYNDROME GENE RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO A DOWN SYNDROME GENE |
摘要 |
<p>The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of a Down Syndrome Gene, in particular, by targeting natural antisense polynucleotides of a Down Syndrome Gene. The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of Down Syndrome Genes.</p> |
申请公布号 |
EP2446037(A2) |
申请公布日期 |
2012.05.02 |
申请号 |
EP20100792668 |
申请日期 |
2010.06.24 |
申请人 |
OPKO CURNA, LLC |
发明人 |
COLLARD, JOSEPH;KHORKOVA SHERMAN, OLGA |
分类号 |
C12N15/113;A61K31/713;A61K48/00;A61P25/00;C12N15/63 |
主分类号 |
C12N15/113 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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