发明名称 |
Camptothecin derivatives and uses thereof |
摘要 |
The present invention provides two new camptothecin derivatives, which were identified as S,R- and S,S-topotecan lactates, respectively. Both compounds have anticancer activities. Pharmaceutical compositions of the new camptothecin derivatives, and cancer therapies with the new camptothecin derivatives or their pharmaceutical compositions were also provided. |
申请公布号 |
US8168648(B2) |
申请公布日期 |
2012.05.01 |
申请号 |
US20100718764 |
申请日期 |
2010.03.05 |
申请人 |
KUO MIN-WEN;CHAN YUNG-HSU;TSENG YUN-LONG;LIEW SIONG-TERN;HONG KEELUNG;TAIWAN LIPOSOME CO., LTD.;TLC BIOPHARMACEUTICALS, INC. |
发明人 |
KUO MIN-WEN;CHAN YUNG-HSU;TSENG YUN-LONG;LIEW SIONG-TERN;HONG KEELUNG |
分类号 |
A61K31/4745;C07D491/22 |
主分类号 |
A61K31/4745 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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