发明名称 |
METHOD OF VERIFYING DIAGNOSIS OF PHEOCHROMOCYTOMA AND/OR PARAGANGLIOMA IN PATIENTS WITH EARLIER DETECTED LEVEL OF DAILY CONJUGATED METANEPHRINE AND/OR CONJUGATED NORMETANEPHRINE EXCRETION, EXCEEDING UPPER NORM LIMIT |
摘要 |
FIELD: medicine. ^ SUBSTANCE: in patients with earlier detected excess of upper norm limit of level of daily conjugated metanephrine and/or conjugated normetanephrine excretion level of daily excretion of conjugated metanephrine and/or conjugated normetanephrine is determined in sample of collected urine at the background of clonidine intake. Sample is positive if the level of daily excretion of conjugated normetanephrine and/or conjugated metanephrine in sample of collected urine is higher than upper norm limit. Claimed method of diagnosis verification possesses high sensitivity and specificity. ^ EFFECT: method application makes it possible to avoid carrying out unjustified surgery in patients with essential arterial hypertension and hormonally non-active formation of adrenal gland. |
申请公布号 |
RU2449288(C1) |
申请公布日期 |
2012.04.27 |
申请号 |
RU20110101229 |
申请日期 |
2011.01.13 |
申请人 |
FEDERAL'NOE GOSUDARSTVENNOE UCHREZHDENIE EHNDOKRINOLOGICHESKIJ NAUCHNYJ TSENTR MINISTERSTVA ZDRAVOOKHRANENIJA I SOTSIAL'NOGO RAZVITIJA ROSSIJSKOJ FEDERATSII |
发明人 |
DEDOV IVAN IVANOVICH;MEL'NICHENKO GALINA AFANAS'EVNA;TROSHINA EKATERINA ANATOL'EVNA;BEL'TSEVICH DMITRIJ GERMANOVICH;JUKINA MARINA JUR'EVNA;KUZNETSOV NIKOLAJ SERGEEVICH;VANUSHKO VLADIMIR EHDUARDOVICH;LYSENKO MAR'JANA ANATOL'EVNA;IL'IN ALEKSANDR VIKTOROVICH |
分类号 |
G01N33/53 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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