| 发明名称 |
Improvement of cell growth in cells deficient in the enzyme dihydrofolate reductase |
| 摘要 |
A method for improving cell growth of a cell line by the introduction of a dihydrofolate reductase (DHFR) expression cassette to increase the activity of DHFR, whereby the DHFR is not used as a selection or amplification maker.
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| 申请公布号 |
NZ579204(A) |
申请公布日期 |
2012.04.27 |
| 申请号 |
NZ20080579204 |
申请日期 |
2008.01.22 |
| 申请人 |
BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG |
发明人 |
KAUFMANN, HITTO;FLORIN, LORE;BECKER, ERIC |
| 分类号 |
C12N9/06;C12N5/10;C12N15/66 |
主分类号 |
C12N9/06 |
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