The invention related to an in vitro population of cells comprising (i) a motor neuron comprising a transgene; said transgene encoding a photosensitive protein capable of triggering or suppressing an action potential upon illumination with light of cognate wavelength; and (ii) an astrocyte. The invention also provides an implantable device comprising a population of cells as described above, wherein said device is structured to retain the cell bodies within the device.
申请公布号
WO2012052727(A2)
申请公布日期
2012.04.26
申请号
WO2011GB01518
申请日期
2011.10.21
申请人
KING'S COLLEGE LONDON;DEGENAAR, PATRICK;LIEBERAM, IVO;GREENSMITH, LINDA;IMPERIAL INNOVATIONS LIMITED;UCL BUSINESS PLC