发明名称 |
NOVEL MONTELUKAST 4-HALOBENZYLAMINE SALT AND METHOD FOR PREPARING MONTELUKAST SODIUM SALT BY USING THE SAME |
摘要 |
Disclosed are a novel montelukast 4-halobenzylamine salt, and a method for preparing a montelukast sodium salt by using the same. In the disclosed method, a montelukast 4-halobenzylamine salt represented by Formula 2 or a montelukast sodium salt represented by Formula 1 is prepared by obtaining a compound represented by Formula 3 from a compound represented by Formula 5, in the same reactor, without an additional obtaining process. (Formular I and II should be inserted here) In Formula 2, X represents F, CI, Br or I. |
申请公布号 |
WO2012015255(A3) |
申请公布日期 |
2012.04.26 |
申请号 |
WO2011KR05566 |
申请日期 |
2011.07.28 |
申请人 |
DONG KOOK PHARM. CO., LTD;KWON, HYUK CHUL;HONG, YEON JU;RHO, MAN DONG;CHA, KYUNG HOI |
发明人 |
KWON, HYUK CHUL;HONG, YEON JU;RHO, MAN DONG;CHA, KYUNG HOI |
分类号 |
C07D215/18;A61K31/47;A61P11/06 |
主分类号 |
C07D215/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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