发明名称 |
PYRIDINE DERIVATIVE HAVING ANTI-HELICOBACTER PYLORI ACTIVITY |
摘要 |
The object is to provide an excellent pharmaceutical having an anti-Helicobacter pylori activity. Disclosed is a novel pyridine derivative represented by the following general formula (I): (see formula I) wherein R represents a linear or branched hydroxyalkyl group having 5 to 10 carbon atoms, or a pharmaceutically acceptable salt thereof, which has a potent antibacterial activity against H. pyroli (Helicobacter pyroli). Examples of the disease which can be prevented/treated by administration of a pharmaceutical agent comprising the compound include gastritis, gastric ulcer, duodenal ulcer, gastric MALT lymphoma, gastric hyperplastic polyp, development of gastric cancer after endoscopic resection of the early stage of gastric cancer and the like.
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申请公布号 |
CA2645467(C) |
申请公布日期 |
2012.04.24 |
申请号 |
CA20072645467 |
申请日期 |
2007.03.07 |
申请人 |
ARIGEN PHARMACEUTICALS, INC. |
发明人 |
ITO, MASAHARU;YAMAMOTO, MASAICHI |
分类号 |
C07D401/12;A61K31/4439;A61K45/00;A61K47/36;A61P1/04;A61P1/18;A61P31/04;A61P35/00;A61P43/00 |
主分类号 |
C07D401/12 |
代理机构 |
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