METHOD FOR PRODUCING ACTIVE FRAGMENT OF HUMAN ALPHA-FETOPROTEIN

摘要

FIELD: medicine. ^ SUBSTANCE: what is offered is a method for recovery and purification of a fragment of human alpha-fetoprotein. The method involves recovery of inclusion bodies containing a target protein from a producer strain biomass, solubilisation followed by renaturation and purification of the active fragment of human alpha-fetoprotein. ^ EFFECT: invention is applicable for producing the active fragment of human alpha-fetoprotein for the purpose of making anticancer preparations of directed action for selective tumour cell destruction. ^ 5 dwg