发明名称 |
PROCESS FOR PRODUCING FLUROCYTIDINE DERIVATIVES |
摘要 |
<p>A process for making a capecitabine or its derivative comprising (a) reacting a compound of the formula (II): wherein each of R1 and R2 independently represents a hydroxyl protecting group, with an acylating agent of formula (III): X—C(═O)—R3, wherein X is an acyl activating group in an organic solvent to produce an acylated compound; (b) deprotecting the acylated compound to obtain the compound of formula (I); and (c) purifying the compound of formula (I) with a solvent.</p> |
申请公布号 |
KR20120037932(A) |
申请公布日期 |
2012.04.20 |
申请号 |
KR20127000421 |
申请日期 |
2010.07.21 |
申请人 |
SCINOPHARM TAIWAN, LTD. |
发明人 |
HU TSUNG CHENG;HUANG HONG TSUNG |
分类号 |
C07H19/067;C07D239/47;C07D239/553;C12P19/00 |
主分类号 |
C07H19/067 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|