发明名称 |
HERPES SIMPLEX VIRUS MUTANT ICP0 |
摘要 |
A mutant herpesvirus that has a mutated gene that encodes a mutant infected cell protein 0 (ICPO) can be used in therapeutic methods as well as in diagnostics and research experiments. The encoded mutant ICPO protein can be altered in one or more regions of ICPO that are substantially conserved between two or more herpesviruses and/or within a phosphorylation region. The mutant herpesvirus can be substantially avirulent and immunogenic. |
申请公布号 |
WO2011126856(A3) |
申请公布日期 |
2012.04.19 |
申请号 |
WO2011US30372 |
申请日期 |
2011.03.29 |
申请人 |
UNIVERSITY OF KANSAS;SOUTHERN ILLINOIS UNIVERSITY;DAVIDO, DAVID;HALFORD, WILLIAM |
发明人 |
DAVIDO, DAVID;HALFORD, WILLIAM |
分类号 |
C12N15/38;A61K39/245;A61P31/12;C12N7/01 |
主分类号 |
C12N15/38 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|