发明名称 Modulation of apolipoprotein C-III expression
摘要 Compounds, compositions and methods are provided for modulating the expression of apolipoprotein C-III. The compositions comprise oligonucleotides, targeted to nucleic acid encoding apolipoprotein C-III. Methods of using these compounds for modulation of apolipoprotein C-III expression and for diagnosis and treatment of disease associated with expression of apolipoprotein C-III are provided.
申请公布号 EP2441449(A1) 申请公布日期 2012.04.18
申请号 EP20110185507 申请日期 2004.04.15
申请人 ISIS PHARMACEUTICALS, INC. 发明人 CROOKE, ROSANNE M.;GRAHAM, MARK J.;LEMONIDIS TARBET, KRISTINA M.;DOBIE, KENNETH
分类号 A61K31/00;A61K38/00;C12N15/113 主分类号 A61K31/00
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