发明名称 |
Modulation of apolipoprotein C-III expression |
摘要 |
Compounds, compositions and methods are provided for modulating the expression of apolipoprotein C-III. The compositions comprise oligonucleotides, targeted to nucleic acid encoding apolipoprotein C-III. Methods of using these compounds for modulation of apolipoprotein C-III expression and for diagnosis and treatment of disease associated with expression of apolipoprotein C-III are provided. |
申请公布号 |
EP2441449(A1) |
申请公布日期 |
2012.04.18 |
申请号 |
EP20110185507 |
申请日期 |
2004.04.15 |
申请人 |
ISIS PHARMACEUTICALS, INC. |
发明人 |
CROOKE, ROSANNE M.;GRAHAM, MARK J.;LEMONIDIS TARBET, KRISTINA M.;DOBIE, KENNETH |
分类号 |
A61K31/00;A61K38/00;C12N15/113 |
主分类号 |
A61K31/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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