发明名称 |
Methods for treating neurological deficits |
摘要 |
The present invention features methods and compositions for treating a patient who has a neurological deficit. The method can be carried out, for example, by contacting (in vivo or in culture) a neural progenitor cell of the patient's central nervous system (CNS) with a polypeptide that binds the epidermal growth factor (EGF) receptor and directing progeny of the proliferating progenitor cells to migrate en masse to a region of the CNS in which they will reside and function in a manner sufficient to reduce the neurological deficit. The method may include a further step in which the progeny of the neural precursor cells are contacted with a compound that stimulates differentiation.
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申请公布号 |
US8158578(B2) |
申请公布日期 |
2012.04.17 |
申请号 |
US20100869468 |
申请日期 |
2010.08.26 |
申请人 |
REID JAMES STEVEN;FALLON JAMES H.;NEUROREPAIR, INC. |
发明人 |
REID JAMES STEVEN;FALLON JAMES H. |
分类号 |
A61K38/00;A61K45/06;A61B5/00;A61K38/18;A61K38/22;A61K49/00;A61P25/28;A61P27/02;C07K14/475;C07K14/48 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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地址 |
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