Peptides with the capacity to bind to transforming growth factor &bgr;1 (TGF-&bgr;1)

摘要

The described peptides possess the capacity to bind to Transforming Growth Factor TGF-&bgr;1 (TGF-&bgr;1), and are potential inhibitors of the biological activity of TGF-&bgr;1 through direct binding to this cytokine. These peptides can be used in the treatment of diseases or pathological alterations based on excessive or deregulated TGF-&bgr;1 expression, e.g., liver fibrosis, pulmonary fibrosis, corneal fibrosis and haze.