The present invention provides erythropoietin derived peptides which bind the erythropoietin receptor and inhibit EPO-induced cell proliferation. The invention further provides pharmaceutical compositions comprising same, and uses thereof in the treatment of primary and secondary erythrocytosis as well as for inhibiting undesirable cell proliferation induced by erythropoietin receptor in patients treated with erythropoietin.
申请公布号
WO2012046238(A2)
申请公布日期
2012.04.12
申请号
WO2011IL00788
申请日期
2011.10.06
申请人
RAMOT AT TEL-AVIV UNIVERSITY LTD.;OPMOP LTD.;LIRON, TAMAR;SOUROUJON, MIRIAM;NEUMANN, DRORIT