1-Aryloxy-2-hydroxy-3-isopropylaminopropane derivs. - beta-adrenolytic agents

摘要

Optically active and racemic substd. 1-aryloxy-2-hydroxy-3-isopropylaminopropane derivs. (I) and their salts R=hal-, straight or branched C1-4 alkyl- or alkoxy-, nitro-, amino-, hydroxy-, nitrile-, C2-4 acyl, methylenedioxy-, aralkyloxy- x=1-3 When x=2 or 3 the R-substit. can be the same or different When x = 1 R cannot be o-hal-, o-methoxy-, o-methyl When x=2 R cannot be 2,6-dimethyl. particularly 1-(2-nitrilophenoxy)2-hydroxy 3-isopropylaminopropane (II) and its salts. beta-Adrenolytic: treatment of heart arrythmia particularly tachycardia and bradycardia.