发明名称 |
CYCLOHEXANE DERIVATIVE COMPOUND |
摘要 |
<p>The purpose of the present invention is to find a therapeutic and/or prophylactic agent for gastrointestinal disorders and so on, said agent having an excellent activity and a high safety. A compound represented by general formula (I) or a pharmacologically acceptable salt of the same. In general formula (I): A represents an optionally substituted phenylene group; B represents an optionally substituted 4- to 10-membered heterocyclic group, an optionally substituted C6-10 aryl group or an optionally substituted C3-10 cycloalkyl group; R1 represents a hydrogen atom or a C1-3 alkyl group; R2 represents a hydrogen atom or a C1-3 alkyl group; R3 represents a C1-6 alkyl group, a C3-10 cycloalkyl group, a C1-3 alkoxy C1-3 alkyl group or a C1-3 hydroxyalkyl group; R4 represents a hydrogen atom, a C1-6 alkyl group or a halogen atom; n is an integer of 1 to 4; and X represents methylene, -O-, -NH-, -N(C1-3 alkyl)-, -C(=O)-,-S-, -S(O)-, -S(O2)- or a single bond.</p> |
申请公布号 |
CA2812898(A1) |
申请公布日期 |
2012.04.05 |
申请号 |
CA20112812898 |
申请日期 |
2011.09.26 |
申请人 |
DAIICHI SANKYO COMPANY, LIMITED |
发明人 |
TODA, NARIHIRO;TAKANO, RIEKO;SHIDA, TAKAHIRO;KATAGIRI, TAKAHIRO;IWAMOTO, MITSUHIRO;ASHIDA, SHINJI;YAMAZAKI, MAMI |
分类号 |
C07D213/64;A61K31/495;A61K31/496;A61P1/00;A61P1/04;A61P1/10;A61P1/14;C07D241/04;C07D295/12;C07D401/12 |
主分类号 |
C07D213/64 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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