发明名称 Methods of using alpha-methylglucoside (AMG) as an indicator for glucose absorption and excretion
摘要 Presented here are methods using alpha-methylglucoside (AMG) in vivo as an indicator for glucose absorption from the gastrointestinal (GI) system or glucose excretion in the urine after oral administration of AMG. The methods find use in, for example, but not limited to, determining the effect of a sodium-dependent glucose transporter (SGLT) inhibitor in an animal, comparing the differences in the effects of a first and second SGLT inhibitor in an animal, and diagnosing a disease associated with glucose absorption from the gastrointestinal (GI) system or glucose excretion from the kidney in an animal.
申请公布号 US8147801(B2) 申请公布日期 2012.04.03
申请号 US20100881695 申请日期 2010.09.14
申请人 DEMAREST KEITH T.;LENHARD JAMES M.;LEO GREGORY C.;LIANG YIN;MARTIN TONYA L.;JANSSEN PHARMACEUTICA, N.V. 发明人 DEMAREST KEITH T.;LENHARD JAMES M.;LEO GREGORY C.;LIANG YIN;MARTIN TONYA L.
分类号 A61K49/00 主分类号 A61K49/00
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