发明名称 Tricyclic fused compounds useful as protein kinase inhibitors
摘要 The disclosure relates to dihydro-imidazol derivatives of formula (I), wherein the variables are as defined in the specification; pharmaceutically acceptable compositions comprising these compounds and methods of using the compositions in the treatment of various disorders in non-human animals; and processes for preparing these compounds. These compounds are useful as inhibitors of protein kinases and are suitable for treating a proliferative disorder (such as melanoma, myeloma, leukemia, lymphoma, neuroblastoma, or a cancer selected from colon, breast, gastric, ovarian, cervical, lung, central nervous system (CNS), renal, prostate, bladder, or pancreatic), a neurodegenerative disorder, an autoimmune disorder, an inflammatory disorder, or an immunologically mediated disorder in a non-human animal.
申请公布号 NZ577638(A) 申请公布日期 2012.03.30
申请号 NZ20070577638 申请日期 2007.12.14
申请人 VERTEX PHARMACEUTICALS, INC. 发明人 CHARRIER, JEAN, DAMIEN;KAY, DAVID;KNEGTEL, RONALD
分类号 C07D475/12 主分类号 C07D475/12
代理机构 代理人
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