<p>The present invention relates to a method of in vivo optical imaging, of the blood vessels and/or blood pool of a mammalian subject, which comprises an optical imaging contrast agent. The optical imaging agents comprise conjugates of far-red or near-infrared dyes with synthetic polyethyleneglycol (PEG) polymers having a molecular weight in the range 15-45 kDa. Also disclosed are methods of treatment monitoring, methods of diagnosis and medical uses involving the contrast agents.</p>
申请公布号
WO2012038489(A1)
申请公布日期
2012.03.29
申请号
WO2011EP66464
申请日期
2011.09.21
申请人
GE HEALTHCARE AS;HEALEY, ANDREW;BENDIKSEN, RAGNAR;SOOD, ANUP;BALINOV, BALIN