RECOMBINANT VIRAL VECTORS AND METHODS FOR INDUCING AN IMMUNE RESPONSE TO YELLOW FEVER VIRUS
摘要
<p>The present invention relates to recombinant viral vectors and methods of using the recombinant viral vectors to induce an immune response to yellow fever virus. The invention provides recombinant viral vectors based on the non-replicating modified vaccinia virus Ankara or based on a D4R-defective vaccinia virus. When administered according to methods of the invention, the recombinant viral vectors induce a broad immune response to yellow fever virus and demonstrate an excellent safety profile.</p>
申请公布号
CA2811739(A1)
申请公布日期
2012.03.29
申请号
CA20112811739
申请日期
2011.09.22
申请人
BAXTER INTERNATIONAL INC.;BAXTER HEALTHCARE S.A.
发明人
FALKNER, FALKO-GUNTER;SCHAFER, BIRGIT;HOLZER, GEORG;BARRETT, P. NOEL;EHRLICH, HARTMUT