| 发明名称 |
PREPARATION OF (R)- AND (S)-N-(3, 4-DIFLUORO-2-(2-FLUORO-4-IODOPHENYLAMINO)--6-METHOXYPHENYL) -1- (2, 3-DIHYDROXYPROPYL)CYCLOPROPANE-1-SULFONAMIDE AND PROTECTED DERIVATIVES THEREOF |
| 摘要 |
The present invention relates to the preparation of (R)-N-(3,4-difluoro-2-(2-fluoro-4-iodophenylamino)-6-methoxyphenyl)-1-(2,3-dihydroxypropyl)cyclopropane-1-sulfonamide and (S)-N-(3,4-difluoro-2-(2-fluoro-4-iodophenylamino)-6-methoxyphenyl)-1-(2,3-dihydroxypropyl)cyclopropane-1-sulfonamide. (I) |
| 申请公布号 |
SG177535(A1) |
申请公布日期 |
2012.03.29 |
| 申请号 |
SG20120000964 |
申请日期 |
2010.07.10 |
| 申请人 |
ARDEA BIOSCIENCES, INC. |
发明人 |
MADERNA, ANDREAS;VERNIER, JEAN-MICHEL |
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