发明名称 PROCEDIMIENTO PARA LA PREPARACION DE NUEVAS 3-AMINO-4-HALO GENO - SIDNONIMINAS.
摘要 <p>1,219,254. Sydnonimine derivatives. BOEHRINGER INGELHEIM G.m.b.H. 26 March, 1969 [26 March, 1968], No. 15910/69. Heading C2C Compounds of the general formula (R 1 , 2 = alkyl, cycloalkyl, aralkyl optionally substituted by CH 3 or halogen, heterocyclic ring linked via alkylene chain to N, or -NR 1 R 2 = heterocyclic ring optionally containing more than one heteroatom and/or being substituted by CH 3 ; R 3 = H, -COR 4 (R4 = alkyl, cycloalkyl, Ph, halophenyl, alkoxy, unsubstituted or substituted nitrogen-containing heterocyclic ring); Hal = halogen) and their acid addition salts are prepared by halogenating a compound of the formula or an acid addition salt thereof, optionally followed by deacylation and/or salt formation. The preparation of the starting materials by standard methods is described. The above compounds are hypotensive agents, and the salts may be administered in the form of pharmaceutical preparations containing them in association with a carrier.</p>
申请公布号 ES376981(A1) 申请公布日期 1972.05.01
申请号 ES19810003769 申请日期 1970.02.27
申请人 C. H. BOEHRINGER SOHN 发明人
分类号 A61K31/00;A61K31/41;A61K31/445;A61K31/47;A61K31/535;C07D271/04;C07D413/04;C07D413/12;(IPC1-7):07D/;61K/ 主分类号 A61K31/00
代理机构 代理人
主权项
地址