发明名称 |
ANTI-IL-3RA ANTIBODY FOR USE IN TREATMENT OF BLOOD TUMOR |
摘要 |
The present invention provides an antibody to human IL-3Rα chain, which does not inhibit IL-3 signaling and binds to B domain of the human IL-3Rα chain but does not bind to C domain of the human IL-3Rα chain; a composition for preventing or treating a blood tumor in which a cell expressing IL-3Rα is found in bone marrow or peripheral blood of a subject, which comprises the antibody to human IL-3Rα as an active ingredient; and a method for treating a blood tumor in which a cell expressing IL-3Rα is found in bone marrow or peripheral blood, which comprises administering, to a subject, a composition comprising the IL-3Rα antibody as an active ingredient.
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申请公布号 |
US2012070448(A1) |
申请公布日期 |
2012.03.22 |
申请号 |
US201013266603 |
申请日期 |
2010.04.27 |
申请人 |
TAWARA TOMONORI;TAKAYANAGI SHINICHIRO;INAGAKI YOSHIMASA;KYOWA HAKKO KIRIN CO., LTD |
发明人 |
TAWARA TOMONORI;TAKAYANAGI SHINICHIRO;INAGAKI YOSHIMASA |
分类号 |
A61K39/395;A61P35/00;C07K16/28 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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