METHOD FOR EXTRACTION OF NON-DENATURATED TYPE-II COLLAGEN HAVING ACTIVE EPITOPE

摘要

PROBLEM TO BE SOLVED: To provide a method for efficiently mass-extracting the epitope in a non-denaturated type-II collagen while keeping the epitope active, and to provide a food or drink using the resultant water-soluble non-denaturated type-II collagen subjected to the extraction by the method.

SOLUTION: The method for extracting an active epitope in a water-soluble non-denaturated type-II collagen includes: a step of subjecting an animal-derived cartilage to a first extraction at 50°C or lower using an acidic solution; and a step of adding pepsin to the resultant acidic solution followed by subjecting the resultant cartilage to a second extraction at 40°C or lower.

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