PEPTIDES INCREASING THE SECRETION AND/OR EXPRESSION OF AT LEAST ONE GASTROINTESTINAL MUCIN AND/OR INDUCING AN INCREASE IN THE POPULATION OF MUCUS CELLS OR PANETH CELLS
摘要
The invention relates to a polypeptide including or consisting of SEQ ID NO: 1, or a sequence at least 80% identical to SEQ ID NO: 1, or a sequence of at least 4 consecutive amino acids included in SEQ ID NO: 1, wherein said polypeptide has at least one effect selected from: inducing the expression and/or the secretion of at least one gastrointestinal mucin; and inducing the expression and/or the secretion of at least one intestinal defense molecule expressed by Paneth cells; and inducing an increase in the population of mucus cells and/or in the population of Paneth cells, with the proviso that the polypeptide does not include the SEQ ID NO: 2 sequence.
申请公布号
EP2430044(A1)
申请公布日期
2012.03.21
申请号
EP20100730816
申请日期
2010.05.12
申请人
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (INRA)