发明名称 |
HIV-1-C RESISTANCE MONITORING |
摘要 |
The present invention relates to methods for the evaluation of HIV-1 Subtype C (HIV-1-C) treatment. The methods are based on evaluating molecular events at the HIV-1-C gag-protease-reverse transcriptase (GPRT) resulting in altered therapeutic efficacy of investigated anti-retroviral compounds. The methods rely on providing HIV-1-C GPRT RNA and evaluating a treatment either through genotyping or phenotyping methods. Said methods may find a use in the field of diagnostics, drug screening, pharmacogenetics and drug development. |
申请公布号 |
US2012064514(A1) |
申请公布日期 |
2012.03.15 |
申请号 |
US201013266973 |
申请日期 |
2010.05.11 |
申请人 |
NAUWELAERS DAVID;STUYVER LIEVEN JOZEF;VIRCO BVBA |
发明人 |
NAUWELAERS DAVID;STUYVER LIEVEN JOZEF |
分类号 |
C12Q1/70;C12N15/63 |
主分类号 |
C12Q1/70 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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