发明名称 LUNG CANCER DIAGNOSTIC POLYPEPTIDE, METHOD FOR DETECTING LUNG CANCER, AND METHOD FOR EVALUATING THERAPEUTIC EFFECT
摘要 <P>PROBLEM TO BE SOLVED: To provide a novel biomarker which can be applied in non-small cell lung cancer diagnosis, in particular, even in early lung cancer diagnosis, since, while SCC, SLX, NSE and ProGRP, besides CEA and CYFRA, are clinically used as tumor markers that can be measured in serum and plasma of lung cancer, NSE and ProGPR are specific to small cell lung cancer and cannot detect non-small cell lung cancer, and, in CEA, CYFRA, SCC and SLX, sensitivity and specificity for detecting non-small cell lung cancer are low and lung cancer at an early stage cannot be detected, so that such tumor markers cannot be applied for use in early lung cancer diagnosis. <P>SOLUTION: In a method for detecting lung cancer, a lung cancer diagnostic polypeptide including a specific amino acid sequence is detected or measured by mass spectrometry. <P>COPYRIGHT: (C)2012,JPO&INPIT
申请公布号 JP2012051822(A) 申请公布日期 2012.03.15
申请号 JP20100194268 申请日期 2010.08.31
申请人 INSTITUTE OF PHYSICAL & CHEMICAL RESEARCH;SHIMADZU CORP 发明人 UEDA YUKITSUGU;NAKAGAWA HIDEWAKI;TOOYAMA ATSUHIKO;SATO TAKAAKI
分类号 C07K14/435;G01N27/62;G01N30/72;G01N30/88;G01N33/68 主分类号 C07K14/435
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