发明名称 ANTIBACTERIAL COMPOSITIONS CONTAINING 3-FLUORO-D-ALANINE TYPE COMPOUND AND N-SUBSTITUTED OSERINE COMPOUND
摘要 <p>PATENT APPLICATION PAPERS OF FREDERICK M. KAHAN for ANTIBACTERIAL COMPOSITIONS CONTAINING 3-FLUORO-D-ALANINE TYPE COMPOUND AND N-SUBSTITUTED CYCLOSERINE COMPOUND Novel antibacterial compositions are prepared by combining 3-fluoro-D-alanine-type compound, such as 3-fluoro-D-alanine and its deutero analogs, and salts and esters thereof, with a 3-fluoro-D-alanine autoantagonistinhibitor such as an N-substituted cycloserine-type compound. The compositions demonstrate highly effective antibacterial action at high levels of dosage of the 3-fluoro-D-alanine component and, in addition, possess a remarkable synergistic antibacterial action.</p>
申请公布号 CA1039191(A) 申请公布日期 1978.09.26
申请号 CA19740205968 申请日期 1974.07.30
申请人 MERCK & CO., INC. 发明人 KAHAN, FREDERICK M.
分类号 A61K31/42;C07D261/04;(IPC1-7):61K31/195 主分类号 A61K31/42
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