摘要 |
<p>PATENT APPLICATION PAPERS OF FREDERICK M. KAHAN for ANTIBACTERIAL COMPOSITIONS CONTAINING 3-FLUORO-D-ALANINE TYPE COMPOUND AND N-SUBSTITUTED CYCLOSERINE COMPOUND Novel antibacterial compositions are prepared by combining 3-fluoro-D-alanine-type compound, such as 3-fluoro-D-alanine and its deutero analogs, and salts and esters thereof, with a 3-fluoro-D-alanine autoantagonistinhibitor such as an N-substituted cycloserine-type compound. The compositions demonstrate highly effective antibacterial action at high levels of dosage of the 3-fluoro-D-alanine component and, in addition, possess a remarkable synergistic antibacterial action.</p> |