发明名称 |
METHOD AND DEVICE FOR COMBINED DETECTION OF VIRAL AND BACTERIAL INFECTIONS |
摘要 |
Devices and methods incorporate lysis agents into a point-of-care testing device. The sample is loaded, and then the sample travels until it encounters a lysis agent. The lysis agent is preferably pre-loaded onto the collection device. In a preferred embodiment, the initially lysis agent is localized between the sample application zone and the conjugate zone. The lysis agent is preferably soluble or miscible in the sample transport liquid, and the lysis agent is solubilized and activated upon contact with the sample transport liquid. The sample transport liquid then contains both lysis agent in solution or suspension and sample components in suspension. Any lysis-susceptible components in a sample, then being exposed in suspension to the lysis agent, are themselves lysed in situ. The running buffer then carries the analyte, including any lysis-freed components, to the detection zone. |
申请公布号 |
EP2335072(A4) |
申请公布日期 |
2012.03.14 |
申请号 |
EP20090815363 |
申请日期 |
2009.09.22 |
申请人 |
RAPID PATHOGEN SCREENING INC. |
发明人 |
SAMBURSKY, ROBERT P.;VANDINE, ROBERT W.;BABU, UMA MAHESH |
分类号 |
G01N33/569;C12Q1/04;G01N33/558 |
主分类号 |
G01N33/569 |
代理机构 |
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代理人 |
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地址 |
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