发明名称 |
Method and apparatus for removing tissue autofluorescence |
摘要 |
Techniques for removing image autoflourescence from fluorescently stained biological images are provided herein. The techniques utilize non-negative matrix factorization that may constrain mixing coefficients to be non-negative. The probability of convergence to local minima is reduced by using smoothness constraints. The non-negative matrix factorization algorithm provides the advantage of removing both dark current and autofluorescence. |
申请公布号 |
US8135187(B2) |
申请公布日期 |
2012.03.13 |
申请号 |
US20080056078 |
申请日期 |
2008.03.26 |
申请人 |
CAN ALI;GERDES MICHAEL JOHN;BELLO MUSODIQ OLATAYO;TAO XIAODONG;PAVAN-WOOLFE FRANCIS EDWARD;BHAGALIA ROSHNI;GENERAL ELECTRIC COMPANY |
发明人 |
CAN ALI;GERDES MICHAEL JOHN;BELLO MUSODIQ OLATAYO;TAO XIAODONG;PAVAN-WOOLFE FRANCIS EDWARD;BHAGALIA ROSHNI |
分类号 |
G06K9/00;A61B1/06 |
主分类号 |
G06K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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