| 发明名称 |
METHOD FOR INHIBITING ACTIVITY AND/OR EXPRESSION OF MATRIX METALLOPROTEINASE, INHIBITING PHOSPHORYLATION OF MITOGEN-ACTIVATED PROTEIN KINASE, AND/OR PROMOTING EXPRESSION OF COLLAGEN USING TORMENTIC ACID |
| 摘要 |
A method for inhibiting the activity of matrix metalloproteinase (MMP), inhibiting the expression of matrix metalloproteinase, inhibiting the phosphorylation of mitogen-activated protein kinase (MAPK), and/or promoting the expression of collagen in a mammal is provided. The method comprises administrating to the mammal an effective amount of an active component selected from a group consisting of a compound of formula (I), a pharmaceutically acceptable salt of the compound, a pharmaceutically acceptable ester of the compound, and combinations thereof:
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| 申请公布号 |
US2012059059(A1) |
申请公布日期 |
2012.03.08 |
| 申请号 |
US20100955336 |
申请日期 |
2010.11.29 |
| 申请人 |
WU JIN-BIN;LIN WEN-CHUAN;HO HUI-YA;CHEN SZE-YING |
发明人 |
WU JIN-BIN;LIN WEN-CHUAN;HO HUI-YA;CHEN SZE-YING |
| 分类号 |
A61K31/191;A61K8/365;A61P17/00;A61Q19/08 |
主分类号 |
A61K31/191 |
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