发明名称 |
Method for the use of [11 C] carbon monoxide in labeling synthesis of 11C-labelled amides using metal amides and photo-induced free radical carbonylation |
摘要 |
Methods and reagents for photo-initiated carbonylation with carbon-isotope labeled carbon monoxide using weakly nucleophilic amines and alkyl/aryl iodides are provided. The resultant carbon-isotope labeled amides are useful as radiopharmaceuticals, especially for use in Positron Emission Tomography (PET). Associated kits for PET studies are also provided. |
申请公布号 |
US8129528(B2) |
申请公布日期 |
2012.03.06 |
申请号 |
US20090478053 |
申请日期 |
2009.06.04 |
申请人 |
ITSENKO OLEKSIY;KIHLBERG TOR;LANGSTROM BENGT;GE HEALTHCARE LIMITED |
发明人 |
ITSENKO OLEKSIY;KIHLBERG TOR;LANGSTROM BENGT |
分类号 |
C07D401/06;A61K51/00 |
主分类号 |
C07D401/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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