| 发明名称 |
Hemiasterlin derivatives and uses thereof in the treatment of cancer |
| 摘要 |
The present invention provides compounds having formula (I): and additionally provides methods for the synthesis thereof and methods for the use thereof in the treatment of cancer, wherein R1-R7, X1, X2, R, Q, and n are as defined herein. |
| 申请公布号 |
US8129407(B2) |
申请公布日期 |
2012.03.06 |
| 申请号 |
US20090394882 |
申请日期 |
2009.02.27 |
| 申请人 |
KOWALCZYK JAMES J.;KUZNETSOV GALINA;SCHILLER SHAWN;SELETSKY BORIS M.;SPYVEE MARK;YANG HU;EISAI INC. |
发明人 |
KOWALCZYK JAMES J.;KUZNETSOV GALINA;SCHILLER SHAWN;SELETSKY BORIS M.;SPYVEE MARK;YANG HU |
| 分类号 |
A61K31/445;C07D295/18;A61K31/16;A61K31/165;A61K31/197;A61K31/40;A61K31/401;A61K31/426;A61K31/427;A61K31/4465;A61K31/454;A61P1/00;A61P9/00;A61P11/00;A61P13/00;A61P35/00;C07C237/12;C07D207/08;C07D207/16;C07D211/32;C07D211/60;C07D277/20;C07D277/56;C07D295/185;C07D401/12;C07D401/14;C07K5/062;C07K5/065;C07K5/078;C07K5/083;C07K5/087;C07K5/097;C07K5/107;C07K7/02;C07K7/06 |
主分类号 |
A61K31/445 |
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