摘要 |
<P>PROBLEM TO BE SOLVED: To provide a material for bone-regeneration with which bone can be effectively regenerated, and a manufacturing method therefor. <P>SOLUTION: The manufacturing method includes a first permeation step of soaking a porous calcium phosphate base material in a low viscosity solution and a second permeation step of soaking the calcium phosphate base material in a collagen solution of higher viscosity than the low viscosity solution after the first permeation step. In the first permeation step and the second permeation step, ultrasonic treatment as well as pressure variation treatment are applied to the calcium phosphate base material. <P>COPYRIGHT: (C)2012,JPO&INPIT |