| 发明名称 |
Compositions and methods for destabilizing lysosomes to increase oncogenic or aberrant protein degradation |
| 摘要 |
The present invention relates to compositions for destabilizing lysosomes to increase the degradation of oncogenic or aberrant proteins for the prevention or treatment of disease. Methods for identifying agents which destabilize lysosomes are also provided as are agents identified in accordance with the screening method. |
| 申请公布号 |
US8124371(B2) |
申请公布日期 |
2012.02.28 |
| 申请号 |
US20040564070 |
申请日期 |
2004.07.30 |
| 申请人 |
KITAREEWAN SUTISAK;SLOBODA ROGER;DMITROVSKY ETHAN;TRUSTEES OF DARTMOUTH COLLEGE |
发明人 |
KITAREEWAN SUTISAK;SLOBODA ROGER;DMITROVSKY ETHAN |
| 分类号 |
C12Q1/37;A61F13/00;A61K31/203;A61K31/4706;A61K33/36;C12Q1/34;G01N33/50 |
主分类号 |
C12Q1/37 |
| 代理机构 |
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代理人 |
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