| 发明名称 |
CONSTRUCTS FOR DELIVERY OF THERAPEUTIC AGENTS TO NEURONAL CELLS |
| 摘要 |
A non-toxic polypeptide, for delivery of a therapeutic agent to a neuronal cell, comprises a binding domain that binds to the neuronal cell, and a translocation domain that translocates the therapeutic agent into the neuronal cell, wherein the translocation domain is not a HN domain of a clostridial toxin and is not a fragment or derivative of a HN domain of a clostridial toxin.
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| 申请公布号 |
CA2392202(C) |
申请公布日期 |
2012.02.28 |
| 申请号 |
CA20002392202 |
申请日期 |
2000.12.04 |
| 申请人 |
MICROBIOLOGICAL RESEARCH AUTHORITY |
发明人 |
SHONE, CLIFFORD CHARLES;SUTTON, JOHN MARK;SILMAN, NIGEL |
| 分类号 |
C12N15/09;C12N15/62;A61K31/711;A61K35/76;A61K38/00;A61K38/43;A61K47/48;A61K48/00;A61P25/00;A61P25/08;A61P25/16;A61P25/28;A61P31/00;A61P31/18;A61P35/00;C07K14/33;C07K14/34;C07K19/00;C12N9/02;C12N9/52;C12N15/87 |
主分类号 |
C12N15/09 |
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