| 发明名称 |
OPTICAL ISOMERS OF DIHYDRO-2,3-BENZODIAZEPINES AND THEIR STEREOSELECTIVE SYNTHESIS |
| 摘要 |
The present invention relates to dihydro-2,3-benzodiazepine compounds of high enantiomeric purity according to the general formula (I), which contain an asymmetric centre at the position 4 of the dihydro-2,3-benzodiazepine compound, and the preparation thereof and the used intermediates as well. These compounds have anti-convulsive A muscle relaxant and neuroprotective effect due their non-competitive AMPA antagonistic properties. |
| 申请公布号 |
EA016087(B1) |
申请公布日期 |
2012.02.28 |
| 申请号 |
EA20080001615 |
申请日期 |
2006.12.29 |
| 申请人 |
EGIS GYOGYSZERGYAR NYILVANOSAN MUEKOEDOE RESZVENYTARSASAG |
发明人 |
LING ISTVAN;BARKOCZY JOZSEF;GREEF ZOLTAN;SZENASI GABOR;GIGLER GABOR;KERTESZ SZABOLCS;SZUCS GYULA;ALBERT MIHALY;KAPUS GABOR;SZABO GEZA;VEGH MIKLOS;AGOSTON MARTA;LEVAY GYORGY;MORICZ KRISZTINA;HARSING LASZLO, GABOR |
| 分类号 |
C07C251/86;A61K31/551;A61P25/00;C07C309/66;C07D243/02;C07D311/58;C07D317/58;C07D491/04;C07D493/04 |
主分类号 |
C07C251/86 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
