发明名称 |
POLY(LACTIC-GLYCOLIC)ACID CROSS LINKED ALENDRONATE (PLGA-ALN) A SHORT TERM CONTROLLED RELEASE SYSTEM FOR STEM CELL DIFFERENTIATION AND DRUG DELIVERY |
摘要 |
The present invention relates to a bisphosphonates and synthetic polymeric carriers to form a sustained release system. The present invention also provides a method for preparing a sustained release system, comprising activation of the synthetic polymeric carriers and the cross linking reaction. The present invention further provides methods for enhancing stem cell differentiation into osteogenic lineage and chondrogenic lineage, which comprise culturing a population of stem cells in specific micro-environments. |
申请公布号 |
US2012045831(A1) |
申请公布日期 |
2012.02.23 |
申请号 |
US20100860377 |
申请日期 |
2010.08.20 |
申请人 |
HO MEI-LING;CHANG JE-KEN;ESWARAMOORTHY RAJALAKSHMANAN;WU SHUN-CHENG;KAOHSIUNG MEDICAL UNIVERSITY |
发明人 |
HO MEI-LING;CHANG JE-KEN;ESWARAMOORTHY RAJALAKSHMANAN;WU SHUN-CHENG |
分类号 |
C12N5/00;C08G63/06 |
主分类号 |
C12N5/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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