In various embodiments, the present invention provides zwitterionic lipids, encapsulants incorporating these zwitterionic lipids and such encapsulants encapsulating one or more bioactive agent. An exemplary bioactive agent is a nucleic acid. Also provided are pharmaceutical formulations of the encapsulants and methods of using such formulations to deliver a bioactive agent to a subject in treating or diagnosing disease in that subject.
申请公布号
WO2012024233(A2)
申请公布日期
2012.02.23
申请号
WO2011US47780
申请日期
2011.08.15
申请人
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA;SZOKA, FRANCIS, C.;WALSH, COLIN;VENDITTO, VINCENT;NGUYEN, JULIANE;PERTTU, EMILY
