发明名称 |
VIRAL NANOPARTICLE CELL-TARGETED DELIVERY PLATFORM |
摘要 |
This invention is a process for the manufacture of a plant viral capsid to be used for the targeted delivery of therapeutics to diseased cells. The process uses a plant virus as the starting material. The choice of the plant virus overcomes a problem in the manufacture of a uniform starting material. The final product has an advantage over other plant virus-based delivery systems in that the plant virus selected has a natural structure that is resistant to breakdown during the delivery process. This system takes advantage of the reversible divalent cation switch that this capsid employs to assemble and disassemble. |
申请公布号 |
US2012039799(A1) |
申请公布日期 |
2012.02.16 |
申请号 |
US20080601736 |
申请日期 |
2008.05.22 |
申请人 |
FRANZEN STEFAN;GUENTHER RICHARD;LOMMEL STEVEN A.;LOO LINA |
发明人 |
FRANZEN STEFAN;GUENTHER RICHARD;LOMMEL STEVEN A.;LOO LINA |
分类号 |
A61K9/00;A61K31/704;A61K51/00;A61P35/00 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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