METHODS AND APPARATUS FOR MASS SPECTROMETRY UTILIZING AN AC ELECTROSPRAY DEVICE

摘要

An alternating current electrospray mass spectrometry device includes an electrospray device having a least one emitter providing a passageway for transmission of an analyte sample. At least one conductive element is in electrical communication with the at least one emitter. A power source generates an alternating current electric field to form a liquid cone at a tip of the emitter and ionizes the analyte sample present in the liquid cone. The frequency of the electric field entrains low mobility ions in the liquid cone. The AC electric field causes the emitter to discharge the liquid cone as a liquid aerosol drop, and a mass spectrometry device analyzes the ionized analyte sample to determine the composition of the contained analyte sample.