1-PYRAZOLO[4,3-C]ISOQUINOLINE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF.

摘要

The invention relates to a compound of formula (I), where: R₁ is a phenyl group optionally substituted by one or more halogen atoms; R₂ is: a hydrogen atom or a halogen atom or a cyano group; a -C(=0)Y group where Y is a hydrogen atom, or a - NH₂ or -OR₃ group; a -C(=S)NH₂ group; a -C(=NH)NH-OH group; a -CH₂OH or -CH₂F group; a -CH=N-OH group; a -CH=CH₂ or -C=C-R₃ group; a H or H R_a group being a hydrogen or (C₁-C₄)alkyl group; R₃ is a hydrogen atom or (C₁-C₄)alkyl group; and R₄ is a -NH₂, (C₁-C₄)alkyl, (C₁-C₄)fluoroalkyl or (C₃- C₇)cycloalkyl group.