发明名称 |
TREATMENT OF MITOCHONDRIAL DISEASES WITH NAPHTHOQUINONES |
摘要 |
Methods of treating, preventing or suppressing symptoms associated with mitochondrial diseases, such as Friedreich's ataxia (FRDA), Leber's Hereditary Optic Neuropathy (LHON), dominant optic atrophy (DOA); mitochondrial myopathy, encephalopathy, lactacidosis, stroke (MELAS), Leigh syndrome or Kearns-Sayre Syndrome (KSS) with compounds of Formula (I) are disclosed. Methods of modulating, normalizing, or enhancing energy biomarkers, as well as compounds useful for such methods are also disclosed. |
申请公布号 |
WO2012019029(A2) |
申请公布日期 |
2012.02.09 |
申请号 |
WO2011US46630 |
申请日期 |
2011.08.04 |
申请人 |
EDISON PHARMACEUTICALS, INC.;JANKOWSKI, ORION, D.;HINMAN, ANDREW, W.;MILLER, GUY, M. |
发明人 |
JANKOWSKI, ORION, D.;HINMAN, ANDREW, W.;MILLER, GUY, M. |
分类号 |
A61K31/122 |
主分类号 |
A61K31/122 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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