发明名称 |
COMPRESSED COMPOSITION |
摘要 |
<p>The purpose of the present invention is to provide a compressed composition which, even when tableted, exhibits excellent retention of coat function or excellent content uniformity. The present invention provides a compressed composition which comprises both coated granules that contain a physiologically active compound or a pharmacologically acceptable salt thereof and a pharmaceutical additive and which is obtained by physically mixing or coating the coated granules with the pharmaceutical additive and then pressing the resulting composition at a low pressure, said pharmaceutical additive containing at least one component selected from the group consisting of hydroxypropyl celluloses with low substitution degrees, lactose, and crystalline cellulose in a total amount of at least 0.5 part by mass per part by mass of the pharmaceutical additive.</p> |
申请公布号 |
WO2012018056(A1) |
申请公布日期 |
2012.02.09 |
申请号 |
WO2011JP67806 |
申请日期 |
2011.08.03 |
申请人 |
EISAI R&D MANAGEMENT CO., LTD.;SAKAMOTO, HIROKAZU;NAGANE, KENTARO;NOHARA, MASAMI |
发明人 |
SAKAMOTO, HIROKAZU;NAGANE, KENTARO;NOHARA, MASAMI |
分类号 |
A61K9/20;A61K31/4439;A61K47/26;A61K47/38;A61P1/04 |
主分类号 |
A61K9/20 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|