发明名称 |
COMPOUNDS FOR TREATING DISORDERS MEDIATED BY METABOTROPIC GLUTAMATE RECEPTOR 5, AND METHODS OF USE THEREOF |
摘要 |
<p>Provided herein are compounds and methods of synthesis thereof. The compounds provided herein are useful for the treatment, prevention, and/or management of various disorders, such as neurological disorders, psychiatric disorders, neuro-muscular disorders, gastrointestinal disorders, lower urinary tract disorder, and cancer. Compounds provided herein modulate the activity of metabotropic glutamate receptor 5 (mGluR5) in the central nervous system or the periphery. Pharmaceutical formulations containing the compounds and their methods of use are also provided herein.</p> |
申请公布号 |
EP2414340(A1) |
申请公布日期 |
2012.02.08 |
申请号 |
EP20100712266 |
申请日期 |
2010.04.01 |
申请人 |
DAINIPPON SUMITOMO PHARMA CO., LTD. |
发明人 |
BURDI, DOUGLAS;SPEAR, KERRY, L.;HARDY, LARRY, WENDELL |
分类号 |
C07D263/56;A61K31/423;A61K31/424;C07D498/04 |
主分类号 |
C07D263/56 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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